False-Positive Aspergillus Galactomannan Antigen Test Results
نویسندگان
چکیده
منابع مشابه
False-positive Aspergillus galactomannan antigenaemia after haematopoietic stem cell transplantation.
OBJECTIVES Although Aspergillus galactomannan (GM) antigen detection is widely applied in the diagnosis of invasive aspergillosis (IA), false-positive reactions with fungus-derived antibiotics, other fungal genera or the passage of dietary GM through injured mucosa are a matter of concern. The aim of this study was to investigate the cumulative incidence and risk factors for false-positive GM a...
متن کاملNew cause for false-positive results with the Pastorex Aspergillus antigen latex agglutination test.
The Pastorex Aspergillus antigen test for detection of Aspergillus galactomannan antigen in the sera of patients with invasive aspergillosis is used in many clinical laboratories. A serum sample contaminated with Penicillium chrysogenum gave a strongly positive reaction (1:128) which was heat stable, was not eliminated by pronase treatment, and was not detected by a normal rabbit globulin contr...
متن کاملPlasmalyte as a cause of false-positive results for Aspergillus galactomannan in bronchoalveolar lavage fluid.
The detection of galactomannan (GM) in the serum of immunocompromised patients is widely used for the early diagnosis of invasive aspergillosis (6). The test may also be useful when applied to bronchoalveolar lavage (BAL) fluid specimens for clinical diagnosis (5), though not FDA approved for this use. One important limiting factor for GM testing is the potential for false-positive results. Mos...
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TO THE EDITOR—In recent years a significant shift in testing has occurred for diagnosing latent tuberculosis (LTB). The adoption of interferon gamma release assays (IGRA) has largely supplanted tuberculin skin test (TST) for both patient testing and employee screening. IGRA have advantages over TST in that they are unaffected by prior vaccination with bacillus Calmette–Guérin (BCG) vaccine and ...
متن کاملFrequent false-positive results of Aspergillus latex agglutination test: transient Aspergillus antigenemia during neutropenia.
BACKGROUND Two serologic assays, Aspergillus latex agglutination testing (LA) and plasma (1-->3)-beta-D-glucan (BDG) measurement, are used when invasive pulmonary aspergillosis (IPA) is suspected. Despite the high specificity of these assays, false-positive results are frequent for neutropenic patients. This study was conducted to evaluate the efficacy of LA and BDG and to investigate the cause...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2004
ISSN: 1058-4838,1537-6591
DOI: 10.1086/422151